THE ENZYME "DIGEST" )
THE NEWSLETTER OF HOUSTON NUTRACEUTICALS, INC MARCH 2004
In This Issue
  • CHEWABLE AFP PEPTIZYDE AVAILABLE IN MARCH!
  • G'DAY, MATE! DR. HOUSTON SPEAKING IN AUSTRALIA!
  • AUTISM ONE IN CHICAGO
  • ENZYME SPOTLIGHT:DPP IV PEPTIDASE
  • HELP!! I CAN'T ORDER ONLINE!!
  • WHAT'S THE BEST WAY TO CONTACT DR. HOUSTON?

  • Spring is on its way here in the beautiful Ozark Mountains of Arkansas! Along with warmer temperatures, rain, jonquils, and baby calves, Spring also means that several large conferences are near. Dr. Devin Houston, owner of Houston Nutraceuticals, will be speaking at several important conferences in the coming months. Information and details are provided below.

    We at HNI want you to know that this forum is here as a resource for information on enzymes and other nutritional issues. What would YOU like to see mentioned or addressed in the HNI newsletter? Let us know by email: info@houstonni.com .

    CHEWABLE AFP PEPTIZYDE AVAILABLE IN MARCH!

    Many parents know the frustration of trying to get a child to swallow a capsule. Chewable tablets have been a good alternative for those children, and many of our customers have asked if our enzymes could be tableted. We are pleased to answer, "YES!". AFP Peptizyde will be available sometime in March as a fruit-flavored soft tablet.

    From a manufacturing viewpoint, tableting is very different from encapsulating a powdered product, usually requiring high pressure to bind the material into a solid tablet. According to Dr. Devin Houston, the pressures involved in forming the tablet can generate heat, which may destroy the enzyme activity. "I had initially been resistant to tableting our products due to concerns about loss of enzyme activity. However, we found a manufacturer that uses the latest state-of-the-art processes for producing a soft tablet with no loss of enzyme potency."

    Dr. Houston notes that it is not possible to get as much enzyme into a tablet as is found in a capsule, so the enzyme load per tablet will be smaller compared to capsules. But many parents divide the capsule doses, so the AFP Peptizyde may be better for those situations. Also, one can simply take more tablets to get the desired dosage.

    For the present, only AFP Peptizyde is offered in tableted form. However, if the demand for Chewable AFP is good, HNI's other products will also follow suit. A definite release date has not been established, please check the website at www.houstonni.com for latest updates.

    G'DAY, MATE! DR. HOUSTON SPEAKING IN AUSTRALIA!
    Dr. Devin Houston, the scientist behind many of the enzyme formulations you see on the market, will be speaking at the Autism Behavioral Intervention Queensland (ABIQ) Conference in Brisbane, Australia on Saturday, May 15, 2004. He is currently scheduled for the 3:30 - 5:00 pm timeslot. For more information about the ABIQ 2004 conference, CLICK HERE.

    Dr. Houston and his wife, Trish, will be traveling throughout Australia and New Zealand from May 9th through May 24th. Cities on the itinerary include Sydney, Brisbane, Cairns in Australia and Queenstown, Christchurch, and Rotorua in New Zealand. The Houstons are very excited about visiting the "land down under" and the chance to meet some of their "Aussie" customers.

    AUTISM ONE IN CHICAGO
    Mark your calendars for May 27th - 30th in Chicago to attend the newest and most exciting conference concerning help for children with autism. Dr. Houston will be speaking in the biomedical interventions track of the conference, as well as exhibiting enzyme products. For more information on Autism One, CLICK HERE.

    For several years, Dr. Houston has been willing to speak with parent groups concerning such topics as nutrition, how dietary enzymes work, and other topics of interest. The Autism One conference will be a chance for parents to hear and see Dr. Houston's presentation on how enzymes affect digestion. We hope those HNI customers who attend will be able to come by our booth and visit.

    ENZYME SPOTLIGHT:DPP IV PEPTIDASE
    This issue's featured enzyme is DPP IV Peptidase. The term "peptidase" actually refers to a large and diverse category of proteolytic enzymes that remove amino acids from proteins in groups of two or more. DPP IV (dipeptidyl peptidase 4) is a protease that removes X--Pro from one end of a protein chain, where "X" represents any amino acid and "Pro" refers to the amino acid proline. DPP IV is the subject of much research in a number of different biomedical forums, and may be an important regulator of certain cellular functions.

    DPP IV is available commercially in purified form, but in dietary enzyme supplements, it is found as an additional enzyme activity in other fungal enzyme preparations. For example, the enzyme blend standardized on lactase activity and sold as "Lactase" may have additional enzymes present at varying levels, including DPP IV. Presently, enzyme product manufacturers do not sell DPP IV as such, but they have ascertained which of their stock enzyme preparations do have DPP IV activity, and that is what is put into most enzyme products. It is misleading to put the term "DPP IV Peptidase" on a product label, because the activity units assigned to Peptidase actually reflect the total proteolytic activity of the enzyme blend, not the specific activity of DPP IV. It is more appropriate to label the enzyme as "Peptidase (with DPP IV)".

    DPP IV is the only known enzyme to break down casomorphin, the exorphin peptide derived from casein. Research indicates that the enzyme removes at least 2 sets of dipeptide amino acids, or 4 amino acids, which disrupts the structure of casomorphin, essentially inactivating the peptide.

    DPP IV may be helpful for those with intolerances to exorphins derived from casein and gluten. DPP IV has only one very specific action, and for it to be effective in dietary interventions, it should be accompanied by several other less specific proteases that "cut" proteins in a different manner from DPP IV.

    HELP!! I CAN'T ORDER ONLINE!!
    We've heard that phrase many times! Many of our customers are frustrated that the HNI online order system apparently doesn't work for them. Conversely, we at HNI have also been frustrated because we could never find a reason for why the system works for so many, but not for others.

    Until now, that is! We have just obtained information that a security update to Microsoft's Internet Explorer may be the cause of the problem. In short, the update was not allowing a valid connection to certain Web servers, including those used by Miva Merchant, our online order gateway.

    To fix the problem, you may need to download a patch for Explorer from Microsoft. You can obtain the download by clicking HERE.

    We prefer our customers to use the online ordering system if at all possible, as it allows us to process orders more efficiently. But the important thing is that you do order, so if online ordering is not your thing, please call our toll-free number, if we don't answer right away, please leave your information on our protected voice mail system, or fax your order to 479- 549-4536. All ordering methods are secured and protected from theft.

    WHAT'S THE BEST WAY TO CONTACT DR. HOUSTON?
    Education and information is an important part of what we do at HNI. Our staff will try their best to answer any question you may have, but the scientific/technical expert is "Dr. Devin", and he is happy to help you with your questions.

    The best way to reach Dr. Houston is through email, as this gives him a chance to research your question, if necessary. Due to the volume of emails received, it may take awhile to receive an answer, but most emails are answered within 1 to 2 days. When on the road, Dr. Houston can usually access his emails. Calling by phone is fine, but please understand we only have two phone lines, and often they are busy due to the heavy volume of ordering. Please feel free to leave a message on the voice mail system.

    Use the information on the website as a first resort, if you don't find your answer there, email or call us.

    Quick Links...

  • HNI Website
  • Enzyme University
  • Enzyme Technical Association

  • Order HNI Products
  • Practical Enzyme Info
  • Bio-Cat Enzymes

  • email: info@houstonni.com
    voice: 866-757-8627
    web: http://www.houstonni.com
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