|Science validates enzymes as gluten-busters|
From Dr. Houston
The gluten-free/casein-free (GFCF) diet has helped many families who deal with autism and the associated GI difficulties, but requires a good deal of effort. Much of that effort is often defeated by unknown contamination of foods with wheat and dairy. Kids often refuse to abide by the constraints of the diet when social pressures intrude (darn those teen years!). But many within the autism community preach the sanctity of the GFCF diet; "do it and put up with it".
By the time I started my own company in 2001, I knew enough of the science to be convinced that certain combinations of fungal-derived proteases could alleviate the problems of wheat and dairy intolerance. While the finding of DPP IV peptidase in commercial enzyme blends was significant, I knew DPP IV alone would not be sufficient as a stand-alone product. Combining DPP IV with other proteolytic enzymes produced a synergistic formulation that broke down gluten, casein, soy and other food proteins in a manner that could decrease the intolerance. I have preached this for eight years now; many have listened and benefited, but others have scoffed.
Now we have evidence from third party research verifying the science of our views. An article in PLoS One, a peer-reviewed journal available online, described decreased gluten toxicity by a combination of DPP IV and another food-grade enzyme, even in the presence of competing proteins such as casein. Gluten is a protein that is extremely difficult for the body's own enzymes to degrade. The addition of "outside" enzymes that are acid-stable cause gluten and other food proteins to "chopped" up more thoroughly. By eliminating the number of large peptides that would ordinarily remain, the chance of immunological response is diminished. This in turn prevents the damage to the gut wall that could occur during intolerance.
This is good news, but many will still insist that there is no alternative to the GFCF diet. My hope is that evidence such as this will open minds and increase the benefits that so many already enjoy.
Q and A with Dr. H
|Your questions answered by Dr. Houston
Q: I have been dicussing enzymes with raw food with a friend. I recall Dr. Houston saying in a webinar that some folks do not do well on a raw food diet because they lack the enzymes to digest them. My friend was saying that she really thought raw foods already have the enzymes needed for digestion. We started the discussion because my kiddo was having tummy problems and we were trying to track the source. I am curious now...talking veggies mainly. Thanks for any insight.
A: While raw foods may be more nutritious, they have only enough enzyme present to facilitate the "rotting" needed to disseminate their seeds in the wild, which occurs over a period of days. Digestion needs to occur within a matter of hours, so the enzyme amounts provided by raw foods are actually not sufficient to have an effect on digestion.
Q: We have been using some general enzymes and your AFP and No-Fenol. My son tested very high for the fungus aspergillus on his recent IgG lab test. Do you process your enzymes in the presence of the fungus aspergillus?
We are not the manufacturers of the enzymes, which are produced in Japan under very strict conditions. I have visited such a factory in Japan and was amazed by the rigorous nature of enzyme purification. Our enzymes, as well as every other company who sells plant-based enzymes, are secreted from Aspergillus oryzae
and A. niger
, which are non-toxic, non-pathogenic strains. However, the fungal matter, spores, and all non-enzyme material are removed very early within the process. These fungi are not related to Candida albicans
, so will not affect or cause yeast problems.
The enzymes undergo 8 - 12 purification steps, the first of which is
filtration of the liquid enzyme from the solid fungal matter. The supernatant, or liquid portion, is further purified until only the enzyme proteins remain. However, since anyone can become allergic to any protein regardless of its source, there is always a chance that some may not tolerate enzyme proteins, but this is very rare, and evident from the first time an enzyme is taken.
AFP-Peptizyde is derived from Aspergillus oryzae, No-Fenol is derived from a different fungi called Trichoderma reseei.
The IgG lab tests would not be able to detect the enzyme proteins,
because they are not the same as the Aspergillus allergen used in the testing, so the fact that he tested high for Aspergillus means he came into contact with a different strain of Aspergillus in the
environment, which is very common.
Bottom line - taking enzymes won't cause a positive reaction on the IgG testing for Aspergillus.
As a side note, many of our customers with mold allergies have no
problem using our enzymes. Others with no mold allergies have shown intolerance to taking the enzymes, so the existence of an allergy to molds does not indicate an intolerance to oral plant enzymes.
A: The only triglyceride that lipase can affect is that found in foods, it can't get into cells and affect systemic triglycerides, except possibly by reducing the amount of triglycerides absorbed from the gut (by the lipase breaking down food triglycerides).
Q: I read that a high lipase product, taken in-between meals, may assist in metabolism of triglycerides and other stuff in the arteries. Is this true?
|Survey shows enzyme success|
Have you participated in our survey? It only takes a few minutes. Click here to participate.
Question: If you challenged the GFCF (Gluten-free/Casein-free) diet, how effective were enzymes?
Early results show:
Very effective, no longer strictly GFCF - 62%
Somewhat effective for some infractions - 30%
Not effective, had to stay totally on diet - 8%
Respondents have given us an abundance of helpful written feedback in the survey. Here is a small sample of responses, each from a different participant:
"Best thing that has EVER happened in regards to food."
"It worked beautifully."
"Still limit his amount of gluten and casein products but nothing like before. We love these!"
"Completely effective, no longer gfcf at all."
"Started with enzymes but still had to put the diet into place according to % above to make changes in my daughter. Behavior is not good if we totally go off the enzymes so I've had her on the enzymes for about 5 years."
"Still avoid some 'trigger' foods."
"We still limit the exposure to gluten and casein, but this allows most foods back into a balanced diet."
"We are now able to eat out without taking food with us to the restaurant!"
"No longer do any GFCF, totally off of it."
"We never ended up on the GFCF diet because the enzymes were so effective."
"Enzymes with pizza do not appear to be completely effective."
"My son eats gluten and casein about 1-2 times a week with enzymes and rarely has a problem."
"We abandoned GFCF when we began enzymes originally. My daughter experienced no worsening of symptoms or health."
"The only foods my son eats has gluten and casein in them. I have noticed a great improvement in my child and his reactions to these foods."
"TriEnza is even more effective than the gfcf diet was for my son!! We are so grateful for this product!!!"
We'll continue to post results as more data is gathered. Click here
to take the survey.
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|TriEnza chewable coming soon|
Look for the new TriEnza chewable version around early September. We will annouce the arrival of this highly anticipated product by email, Twitter, Facebook and our hompage; stay tuned.
|Enzyme events |
Dr. Houston will be speaking/exhibiting at the events below. More info available on our Events Calendar.
- Web Seminar: 9/16/09, 8:00 p.m. ET. Discussion by Dr. Houston on common digestive problems in adults. Live event open to everyone. Click here to reserve your seat.
- Dallas: Exhibitor for DAN! Conference, 10/8-10/11/09.
- Ascot, U.K.: Speaker for Whole Health Learning for Autism and Related Disorders International Conference, 10/24/09.
- Las Vegas: Exhibitor for ACAM Conference (American College for Advancement in Medicine), 11/5-11/7/09.
Group Leaders - Contact Outreach Coordinator Cindy Kelley (866-275-0915) for:
- Live presentations
- Conference calls
- Web seminars
Dr. Devin Houston, Ph.D. enzyme biochemist, speaks at no cost to parent groups and parent conferences.
Click here for calendar details and updates.
Toll free: 866-757-8627