How lipase helps to digest fats

Fats and oils

Lipase enzymes are some of the most important enzymes produced in nature. 

Lipases are found in a variety of sources. They were first discovered in 1846 by Claude Bernard while investigating pancreatic cells. Lipases have since been found in plants, fungi, and microbes. 

The importance of lipase is due to the ability to convert fats and triglycerides to short-chain fatty acids. 

Much research is devoted to finding ways to produce lipase for industrial purposes such as management of waste oils. Now, medical research is focusing on the use of lipase enzymes as therapeutic agents.

Lipases are vital in breaking down the fats and triglycerides in our foods. The human body produces a variety of different lipases, from the mouth to the intestinal tract, for digesting different types of fats.

Deficiency of digestive lipase results in gastrointestinal problems, indigestion, and skin rashes related to digestive allergies. Certain immunological factors are activated by lipases, which has prompted research into the management of certain cancerous tumors.

Dietary lipase supplements are helpful in breaking down fats while they are still held in the stomach. The ability to be active under acidic conditions is the major advantage microbial/fungal lipase supplements have over pancreatic lipases. 

The other advantage of lipase supplements is they don’t require a prescription, while pancreatic lipase typically does. 

Why is it so important to have lipase active in the stomach?

Dietary fats can slow down the emptying of the stomach, which delays digestion of the food mass. This contributes to bloating and stomach distress. 

Acid will continue to be secreted into the stomach as long as the food remains. This can contribute to heartburn and reflux especially with large meals taken during the evening. 

Using a lipase supplement can increase the breakdown of fats in the stomach, which prevents the delay in emptying.

Many are using high-fat diets, such as the Keto Diet and Paleo Diets. These diets may be helpful, but you may find the extra amount of fats and oils in the diet produces unwanted effects, such as increased flatulence and fatty stools. 

The use of lipase supplements, such as Lypazyme, can help digest the fats and produce short-chain fatty acids.

These compounds are the main source of nutrition for cells in the colon, and are considered helpful in reducing the risk of inflammation. 

 

Source: https://www.sciencedirect.com/science/article/pii/S0254629918301029

 


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