How to Get Started With Enzymes

1. I'm not sure where to start ... 

If you don't know what to start with, use a broad-spectrum product:

Zyme Prime or TriEnza.

Zyme Prime is easy to adjust to. Zyme Prime is mild, low in protease (protein digesting enzymes), and has no fruit-based enzymes. It should not cause any discomfort. Excellent starter product for sensitive gut.

If you do not see desired results with Zyme Prime, either increase the dose, add another product (AFP-Peptizyde, or No-Fenol) or switch to TriEnza.

TriEnza is a stronger broad-spectrum product. It contains the enzymes from AFP-Peptizyde for proteins, the enzymes from Zyme Prime for fats & carbohydrates, and 1/2 the enzymes from No-Fenol (Xylanase) for certain fruits and vegetables. TriEnza is higher in proteases than Zyme Prime. TriEnza has DPP IV activity, unlike Zyme Prime, and may be an alternative to the GFCF diet. 

You may want to start dosing TriEnza with one meal per day and increase gradually to 2 capsules per meal. 

2. I need help with the GFCF diet, or need an alternative to the diet... 

Many of our customers use the Gluten-Free Casein-Free (GFCF) diet for their children with special needs. If the parent complains about the difficulty of doing the diets, or the child is wanting more freedom to eat "like his friends do", or I hear the parent wanting to improve gluten- and casein-connected behaviors - then I recommend the high-protease AFP-Peptizyde. One capsule contains potent quantities of DPP IV peptidase plus additional proteases.

AFP-Peptizyde was one of our original products invented as an alternative for the GFCF diet. AFP-Peptizyde and TriEnza are high-protease, with high DPP IV activity. TriEnza is a newer combination product, but requires 2 capsules to equal the protease activity of one AFP-Peptizyde capsule.

Best to start these high-protease products with low and slow dosing. If the child is already on the GFCF diet, then parent should not change the diet until fully adjusted to enzymes.

These products are not used for celiac disease. No enzyme product is available for celiac disease or for "cheating" on a celiac diet, in any form.

If you are concerned about the gluten and/or casein proteins, start with:

AFP Peptizyde (or TriEnza).

3. Loose stools, low weight, picky eater, carb craver, gas & bloating

If I hear phrases like "loose stools", "low weight", "picky eater", "carb craver", "gassy" etc.; then I usually recommend starting with:

Zyme Prime or ZyCarb.

Zyme Prime tends to firm stools. It is excellent at breaking down carbs.  If constipation is a problem, but you still need help with carbohydrates, try ZyCarb. ZyCarb is similar to Zyme Prime, but less firming.

4. Food related intolerances

Skin rashes or rough patches on elbows while not restricting gluten may be indicators of gluten intolerance. We can achieve better digestion of gluten through the use of protease enzymes. 

AFP Peptizyde (or TriEnza) would be suggested. 

5. Is constipation a problem?

If so, then we want to avoid using Zyme Prime alone, as it decreases fecal mass and firms the stools. If this is an issue, try adding our No-Fenol product as it tends to soften the food mass in the gut. ZyCarb, which contains xylanase plus most of the enzymes found in Zyme Prime, may be a better product for those with constipation. 

If Zyme Prime is needed:

No-Fenol can be added to counteract the stool-hardening properties of Zyme Prime.

If No-Fenol softens stools too much, reduce the dose or add Zyme Prime.

Consider Biomuve, our new product for occasional constipation. Biomuve is a combination of the main enzyme from No-Fenol, probiotics and prebiotics. 

6. Does the child have red cheeks and/or ears after eating certain fruits?

This can be a phenolic intolerance that may be helped by using:


"Shiners" under the eyes may also be an indicator that phenolic foods are problem. 

7. Fats or oils causing digestive discomfort?

Lypazyme is formulated to help break down triglyceride fats while still in the stomach. Faster fat breakdown prevents the delay in stomach emptying usually associated with high-fat meals. Lypayzme is helpful when supplementing with fish oils and other sources of beneficial fats. Lypazyme helps prevent gas and bloating from fats and oils.


As with any supplement, results can vary with the individual and there is always the exception. But most can use the above as a guide for starting enzymes. The great thing about enzymes is that they are not harmful at any level of dosing, so you can experiment to find the best combination for your particular needs.

These statements have not been evaluated by the FDA. These products are not intended to diagnose, cure, treat, or prevent any disease. Peptizyde™ is a trademark of Houston Nutraceuticals, Inc.